Porins of Lyme Disease and Relapsing Fever Spirochetes

Porins of Lyme Disease and Relapsing Fever Spirochetes
Thein, Marcus
Preis 43,00inkl. ges. MwSt.
ISBN 978-3-8441-0195-9
Bestell-Nr. 0195C
Gewicht 212 g
Warengruppe Andere Reihen
Sachgruppe Schriften zur Lyme-Borreliose
Einband broschiert
Sprache Englisch
Umfang 140
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Inhaltsverzeichnis

1. Introduction
1.1. The bacterial genus Borrelia
1.2. The Gram-negative cell-envelope
1.3. The Borrelia cell-envelope
1.4 Aims of this work

2. Oms38 is the first identified pore-forming protein in the outer membrane of relapsing fever spirochetes
2.1. Summary
2.2. Introduction
2.3. Materials and Methods
2.4. Results
2.5. Discussion

3. DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates
3.1. Summary
3.2. Introduction
3.3. Materials and Methods
3.4. Results
3.5. Discussion

4. The P66 porin is present in both Lyme disease and relapsing fever spirochetes: A comparison of the biophysical properties of six P66 species
4.1. Summary
4.2. Introduction
4.3. Materials and Methods
4.4. Results
4.5. Discussion

5. The use of nonelectrolytes as molecular tools reveals the channel size and the oligomeric constitution of the Borrelia burgdorferi porin P66
5.1. Summary
5.2. Introduction
5.3. Materials and Methods
5.4. Results
5.5. Discussion

6. Conclusions

Über den Autor

Marcus Thein was born 1979 in Würzburg, Germany. He studied biology from 2000 to 2005 at the Bavarian Julius-Maximilians-University Würzburg. From 2005 to 2008 he did his Ph.D. at the University Würzburg, with several research stays at the University in Umeå, Sweden. From 2008 to 2011 he was a postdoctoral fellow at the Max-Planck-Institute of Developmental Biology, Tübingen, Germany, and since 2011 he is a scientist at the Fraunhofer Institute for Interfacial Engineering and Biotechnology in Stuttgart, Germany.

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